NAD+

NAD+ (nicotinamide adenine dinucleotide) is not actually a peptide. It is a coenzyme central to cellular energy metabolism that happens to be sold through the same research-chemical and wellness channels, which is why it lives in this index. Levels decline with age, and that finding built an injection-and-IV industry well ahead of the human evidence.

What NAD+ does

NAD+ shuttles electrons in the reactions that make cellular energy and serves as a substrate for enzymes tied to DNA repair and cellular aging (sirtuins, PARPs). The age-related decline is well documented; what supplementing it does for healthy humans is far less so.

Injections, IVs, and the evidence gap

Wellness clinics sell NAD+ IV drips and subcutaneous injections for energy, cognition, and “anti-aging.” Human trial evidence for those outcomes is limited and mixed; the strongest supplementation data concerns oral precursors (NMN, NR) rather than injected NAD+ itself, and academic reviews consistently describe the clinical evidence as early.

Tested batches and vendors

Working out reconstitution or syringe units? Use the free peptide calculator, then check your batch’s published test result before trusting the label: in 2024, roughly 43% of research peptides submitted to Janoshik Analytical missed their label claims.

Vendor rankings on PeptideCensus are computed only from publicly published third-party lab results; see the vendor index and how scoring works.

Safety notes

Rapid IV infusion is commonly reported to cause flushing, nausea, and chest tightness, which is why clinics drip it slowly. Gray-market vials carry the same unverified-content risk as everything else in this index.

Common questions

Is NAD+ a peptide?

No. It is a coenzyme. It is indexed here because it is sold through the same vendors and formats as research peptides.

Do NAD+ injections work?

The short answer: the aging biology is real; the human clinical evidence for injected NAD+ benefits is limited and early.

NAD+ vs NMN or NR?

NMN and NR are oral precursors your cells convert toward NAD+; most human supplementation data involves them rather than direct NAD+ injection.

Why do NAD+ prices vary so much?

Format (IV clinic vs vial), dose size, and vendor margin. Compare per-milligram against tested content, not the marketing.

PeptideCensus aggregates publicly published third-party lab results and links every number to its source. Nothing on this page is medical advice; research compounds are not for human use.

Dosing math: use the free peptide calculator to work out reconstitution and syringe units — then check your vial’s published batch result before relying on the label.